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Wageningen University and Research International PhD Position

Applicants are invited to apply for a PhD position in bioinformatics in Netherlands. The funds for this fellowship are available for 18 months. Applications will be evaluated on a continuous basis.

Are you ready for a PhD position in Biotechnology, Bioinformatics, or molecular life sciences? Do you have a strong affinity with both wet lab and computational work? We offer you the chance to give your career a boost in Wageningen!

As a PhD candidate, you will combine state-of-the-art molecular tools available at the hosting lab to build strains, fermentation experiments in small scale (1.5L) bio-reactors, computational modelling of metabolism and analysis of omics and bioreactor data sets. Machine learning and data integration techniques will be used to iteratively refine the designs towards an optimal biocatalyst in our project.

The project is about metabolic modelling which provides a solid foundation both for increased understanding of cellular metabolism, and for tailoring of microbial chassis towards innovative biotechnological applications. In this project we will develop a solution to provide a sustainable replacement of palm-oil that will contribute to meeting the growing demand of oils and fatty acids.

We will use the well-known lipid producer yeasts Cutaneotrichosporon curvatus (formerly known as Cryptococcus curvatus) and Yarrowia lipolytica. Through a combination of model driven experimentation followed by experimental characterization we will develop strategies to control not only the amount but also the chain and or saturation level of the produced fatty acids.

In this project our laboratory will work closely together with the applied research groups of Wageningen Food & Biobased Research, where direct translation towards application will be pursued with several industrial partners.

We offer a full-time position (38 hours), initially for 18 months after which a go/no go decision will be taken on an extension for an additional 30 months.

Gross salary per month 2325,- in the first year rising to 2972,- per month in the fourth year, in accordance with the Collective Labor Agreement Wageningen University (scale P).

Wageningen University & Research stimulates internal career opportunities and mobility with our internal recruitment policy. There are ample opportunities for personal initiative in a learning environment. With us you get a versatile job in an international environment with a pleasant and open working atmosphere.

For more information about this position, please contact Prof. Vtor Martins dos Santos, chair Systems and Synthetic Biology, telephone number +31 317482865 or Prof Jeroen Hugenholtz, Groupleader Microbial Cell Factories, Wageningen Food & Biobased Research, telephone number +31 317485287.

This can be done directly via the application button at the vacancy on our website so that we can process your personal data with your permission. This vacancy is open until Saturday 23rd May 2020.

We are an employer that offers equal opportunities. We are happy to receive applications from all suitably qualified people regardless of race, gender, functional impairment, religion / belief, sexual orientation or age.

We believe that a diverse and inclusive working environment makes us a more relevant, competitive and resilient organization. Click for more information about working at WUR with a functional impairment.

The mission of our University is to explore the potential of nature to improve the quality of life. Within Wageningen University & Research, nine specialised research institutes from the Wageningen Research Foundation and Wageningen University have joined forces to help answer the most important questions in the domain of healthy food and living environment.

With approximately 30 locations, 6,500 employees, and 12,000 students, it is one of the leading organisations in its domain worldwide. An integrated approach to problems and the cooperation between various disciplines are at the heart of the unique approach of Wageningen. We have been named Best Employer in Education category 2019-2020.

The Laboratory of Systems & Synthetic Biology (www.wageningenur.nl/ssb) addresses in an integrated way critical issues and novel biotechnological applications in the areas of Health & Food, BioBased Products and Environment.

Our mission is to contribute to the elucidation [from a Systems Biology perspective] of the mechanisms underlying basic cellular processes, evolution and interactions among microbes and between microbes and their environment (including the human host), and to translate this knowledge [from a Synthetic Biology perspective] into applications of biotechnological, medical and environmental interest.
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