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Postdoc in Computational Metabolomics at Chalmers University of Technology

Chalmers University of Technology, Sweden is inviting applicants to apply for a PhD position in communicable diseases. The funding allows successful candidate to work for three years. The deadline to apply is February 02, 2020.

Information about the research

Studies of the molecular mechanisms underlying interactions between lifetime exposures (e.g. from foods and gut microbiota) and the host are urgently needed for improved understanding of their role in the development and prevention of non-communicable diseases. Metabolomics is a fundamental tool in this research and gives a snapshot of the molecular phenotype. Large amounts of data are being generated and there is great need to develop and apply high-throughput analysis pipelines and novel bioinformatic tools to analyze and integrate metabolomics data with other data domains, such as other Omics. We are now looking for a PostDoc in Computational Metabolomics to identify metabolomic profiles associated with exposures to environmental exposures (food, lifestyle, air, noise, etc) in large untargeted LC-MS-based metabolomics data sets. These data will contain several thousand samples with repeated measures at multiple timepoints. The PostDoc will also be responsible for integration of metabolomics with other Omics data using novel tools for data integration.

-The details of the departmental research activities may be found here.

About the division

The division of Food and Nutrition Science is one of four research divisions at the Department of Biology and Biological Engineering. Food and Nutrition Science is one of the leading units in the area in Sweden with particular strengths in nutritional and computational metabolomics, dietary biomarkers, micronutrient metal nutrition, nutritional immunology as well as marine food science and nutrition. The division has a wide range of modern analytical equipment for chromatography coupled with mass spectrometery, an in vitro human cell laboratory, and a microbiology laboratory. The division has also extensive collaborations with Chalmers Mass Spectrometry Infrastructure and The Swedish NMR center (University of Gothenburg) which are infrastructure facilities with top modern equipment for metabolomics experiments. The division focuses on nutritional solutions for health and disease prevention by studies on the molecular, cellular, and whole-body level. It also has a strong focus on sustainable use of food raw materials and on many different quality aspects of food.

Major responsibilities

This PostDoc position will require a high degree of data analytical competence, including LC-MS data preprocessing, multivariate analysis and multiOmics data integration. The applicant is further expected to contribute to the active software development in the research environment and to apply and develop cutting edge tools for multivariate analysis of repeated measures as well as data integration. There will also be opportunities to contribute to development of AI / machine leaning for metabolomics analysis with the aim to put Chalmers at the forefront in health engineering and precision nutrition.

A successful candidate must demonstrate excellent understanding of the field of computational metabolomics, and will require the ability to execute high quality research efforts with a high degree of independence. The candidate is expected to supervise students, as well as to contribute to the development of the field of computational metabolomics at the intersection between lifetime exposures, including diet, systems biology, bioanalytical chemsitry and software/algorithm development.

Full-time temporary employment. The position is limited to a maximum of two years (1+1).

Qualifications

To qualify for the position of postdoc, you must have a doctoral degree in a relevant field; bioinformatics, metabolomics, computational mass spectrometry, chemometrics. The degree should generally not be older than three years.

You are expected to be somewhat accustomed to teaching, and to demonstrate good potential within research and education.

- Track reckord of high quality research

- Demonstrated ability to conduct high quality research with a high degree of independence

- Proficient R-software usage and software development skills

- Multivariate data analysis

The position requires sound verbal and written communication skills in English.

Chalmers offers a cultivating and inspiring working environment in the dynamic city ofGothenburg.

Read more aboutworking at Chalmersand ourbenefitsfor employees.

Application procedure

The application should be marked with Ref 20190707 and written in English.

CV: (Please name the document as: CV, Surname, Ref.

CV, include complete list of publications

Previous teaching and pedagogical experiences

Two references that we can contact.

Personal letter:(Please name the document as: Personal letter, Family name, Ref. number)

- Introduce yourself

- Describe your previous research fields and main research results

- Describe your future goals and future research focus

Attested copies of completed education, grades and other certificates.

Application deadline: 2 February 2020

Carl Brunius, Associate Professor, Food and Nutrition Science, carl.brunius@chalmers.se

About the department

The Department of Biology and Biological Engineering was founded January 1 2015, and started off with high ambitions. The aim was to grow and become a leading center of innovation by combining the latest research in life sciences with biochemistry. And the department got off to flying start. In its first year, the numbers for publication, citation and external funding have been excellent. The department consists of four divisions, each conducting outstanding research in the areas of industrial biotechnology, systems biology, chemical biology and food science. The overall goal is to help build a sustainable society and improve human health.

Nearly 200 people from 20 countries are currently working at the department. The working environment is characterized by respect, cooperation, responsibility, creativity and job satisfaction.

- To be an attractive environment for top-level researchers in biological engineering

- To deliver top-level research results and innovative solutions for use in a sustainable society - To offer excellent education that develops creative engineers and scientists


Summary:

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