Asst Res Scientist at University of Michigan

University of Michigan, USA is offering postdoctoral associate position in molecular biology. Applicants should apply as soon as possible.

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

The Shea Lab in the Department of Biomedical Engineering at the University of Michigan-Ann Arbor is looking for an Assistant Research Scientist in the joint areas systems biology for the application of chimeric antigen receptor (CAR) T cell design.

Technical: This position will be responsible for applying a high throughput transcription factor activity array to the study of CAR T cells. This project will include fabricating novel CARs and reporters, delivering these constructs to primary T cells, subsequent imaging of these cells after activation, and data analysis related to these experiments. Additional responsibilities include testing of new constructs using rodent models and generating/analyzing single cell RNA-sequencing data related to CAR T cell activation. These include generate preliminary data for grants and having a depth of knowledge in molecular biology and systems biology to function as the "go-to" person in these areas within the lab.

Teaching: This position will be expected to take an active role in mentoring graduate and undergraduate students in the lab with their area of expertise (e.g. data analysis, manuscript preparation, experimental design, etc.)

Management: Manage the existing array technology and facilitate its dissemination to other labs at the University of Michigan and the broader scientific community. This includes supporting the production of new constructs, maintaining the existing library, and assisting with experimental design and data analysis as needed.

Scientific Independence: This position is expected to demonstrate independence and develop a reputation within the field of cell-based immunotherapies. Contribution of expertise and data for grant application is expected as well.

Applicants should have obtained a PhD in an engineering discipline with several years of postdoctoral experience. Demonstrated expertise (e.g. peer-reviewed publications, presentations at national conferences) in living cell arrays, multiple methods of gene delivery (e.g. lentiviral, CRISPR), molecular biology, and high throughput data analysis is expected. Applicants are expected to have the strong communication and management skills necessary to involve students in their project and must work well in a collaborative setting.

The applicant is preferred to have a demonstrated history of acquiring external funding and desire to develop new competitive grant applications from their research.

Michigan Engineering's vision is to be the world's preeminent college of engineering serving the common good. This global outlook, leadership focus and service commitment permeate our culture. Our vision is supported by a mission and values that, together, provide the framework for all that we do. Information about our vision, mission and values can be found at:

The University of Michigan has a storied legacy of commitment to Diversity, Equity and Inclusion (DEI). The Michigan Engineering component of the University's comprehensive, five-year, DEI strategic planalong with updates on our programs and resources dedicated to ensuring a welcoming, fair and inclusive environmentcan be found at:

The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks will be performed in compliance with the Fair Credit Reporting Act.

Job openings are posted for a minimum of seven calendar days. This job may be removed from posting boards and filled anytime after the minimum posting period has ended.

The University of Michigan is an equal opportunity/affirmative action employer.


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