Research Assistant at University of Cambridge

Applicants are invited to apply for a postdoctoral researcher position in molecular biology at University of Cambridge, UK. The funding allows successful candidate to work for 36 months. Applications are welcome before September 05, 2019.

Departments of Paediatrics and Virology, University of Cambridge

Applications are invited for the post of a Research Assistant in the Department of Paediatrics under the lead of Prof Matthias Zilbauer in collaboration with Drs Valeria Lulla and Andrew Firth (Department of Pathology, Division of Virology).

EXCITING RESEARCH: This MRC funded project will investigate the pathophysiology of enteroviruses, using human mucosa derived intestinal epithelial organoids. The work will involve the generation of organoids from primary human samples, their infection with viruses followed by virus titrations and sample analyses, and genetic modification of organoids using CRISPR/Cas9. The successful candidate will also have the opportunity to contribute to the ongoing projects involving intestinal organoids both at the departments of Paediatrics and Virology.

PERSONAL DEVELOPMENT: This post offers a great opportunity for the candidate to develop significant expertise in human organoid culture and molecular virology techniques, and to apply this through participation in this interdisciplinary, translational research project. The successful candidate will be encouraged and fully supported to continue their professional development through the attendance of specific courses and/or conferences as well as a wide range of training opportunities offered by the University of Cambridge.

TEAM WORK: The post-holder will join a diverse, supportive and friendly team of scientists, clinicians and other professionals within the Departments of Paediatrics and Virology. We place a major emphasis on the importance of team work and enjoyable work environment as a foundation and prerequisite for performing internationally leading translational research.

EXPERIENCE: We are seeking a motivated and enthusiastic individual who will contribute their existing expertise whilst seeking to develop new skills. The ideal candidate has experience in tissue culture work and basic molecular biology techniques such as PCR, western blotting or FACS. Previous experience working with viruses is an advantage. Good organisational and interpersonal skills are essential and the candidates must be familiar with the principles of good laboratory practice. Careful observation and accurate record keeping is essential. The post requires occasional out of hours work and therefore a flexible approach to working hours is required.

The general duties/responsibilities of this post include generation and culturing of intestinal organoids, production of conditioned media, tissue processing (e.g. DNA/RNA extraction, PCR, real-time PCR), and maintenance of sample databases. Contribution to laboratory administration such as ordering of reagents and maintenance of equipment will also be expected. Further details can be found in the attached document (Further information).

Funds are available in the first instance for a fixed term of 36 months at 66% FTE or 24 months at 100% FTE (following successful completion of a probation period). Please stipulate in your application if you are applying for Full time or Part time.

Click the ‘Apply’ button below to register an account with our recruitment system (if you have not already) and apply online.

The closing date is 5 September 2019, with the interview date expected to be week commencing 9 September 2019.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.


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