Postdoc Position at University of Cambridge

A new postdoctoral fellowship position in public health is available at University of Cambridge. The funding allows successful candidates to work for 3 years in the first instance. Eligible candidates should submit the applications before September 10, 2019.

The MRC Biostatistics Unit undertakes research on statistical methods and their application to the design, analysis and interpretation of biomedical studies, to advance understanding of the cause, natural history and treatment of disease, and to evaluate public health strategies. A research team under the direction of Dr Chris Wallace aims to develop statistical methods for the analysis of genomic data to understand the human immune system and its dysregulation in relation to the autoimmune diseases (e.g. type 1 diabetes and rheumatoid arthritis) which collectively affect 5% of the population. Our goal is to understand the genes, cells and pathways which underlie autoimmune diseases, the interactions between these pathways, and the relationships between different autoimmune diseases. Better understanding of the aetiology of these diseases is essential to underpin better treatment strategies.

We are seeking an ambitious statistician to contribute to this research team. The post-holder will lead integration of statistical methods for inferring direct and indirect genetic regulation of gene expression with conditional independence approaches to within gene expression data to build gene regulatory networks. To synergise with other projects in the Wallace group, the focus will be on immune cells, particular key driver genes and examining how the networks vary between cell type and state.

Current members are working across a diverse range of projects including genetic association to disease, mechanisms of genomic regulation and modelling of count data from emerging sequencing-based technologies. For further information on the group and our research, see

The group is based in the MRC Biostatistics Unit ( and the University of Cambridge Department of Medicine (, both located within the Cambridge Biomedical Campus. The advertised post will be located in the Biostatistics Unit, but the available interdisciplinary environment offers the applicant the chance to pursue statistical methodology and apply solutions to novel biological datasets in order to address questions of relevance to human autoimmune diseases. Our group has active collaborations within Cambridge (eg Ken Smith) and the nearby Babraham Institute (Peter Fraser and Mikhail Spivakov), but also with the University of Manchester (Wendy Thomson and Steve Eyre) and UCL (Lucy Wedderburn). Please contact with any informal enquiries.

Fixed-term: The funds for this post are available for 3 years in the first instance.

The post is full-time but applications are welcome from those who would like to work flexibly.

Click the ‘Apply’ button below to register an account with our recruitment system (if you have not already) and apply online.

The closing date for applications is Tuesday 10th September with interview date to be confirmed.

Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including e-mail address and phone number, one of which must be your most recent line manager

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.


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