PhD in Vision Sciences Exploring The Relationship Between Visual Pigment Kinetics and Age-related Macular Degeneration Pathology

Cardiff University, UK is inviting excellent students to apply for a PhD position in optometry. Eligible candidates should submit the applications before September 04, 2019.

Applications are invited for a 3-year PhD studentship in Vision Sciences at the School of Optometry and Vision Sciences, funded by the College of Optometrists.

Using technology more usually found in the field of astronomy, we have developed a ground-breaking functional imaging technique known as Imaging Retinal Densitometry (IRD) that can probe outer retinal function in unprecedented detail.

The technology directly measures the regeneration of the light-sensitive visual pigments within the outer retina. This regeneration process, known as the visual cycle, is essential for vision and dictates the rate at which the eye can adapt to darkness. This process is known to be impaired in Age-related Macular Degeneration (AMD), and is a sensitive sign of the condition, but it is not known how the process is affected by common clinical signs of AMD such as drusen. IRD for the first time can map differences across the retina.

In this PhD, you will develop and apply imaging analysis techniques to investigate the relationship between visual pigment kinetics and clinically visible AMD lesions from photography and Optical Coherence Tomography (OCT). Understanding the relationship between clinically visible signs of AMD and IRD measures of outer-retinal function is expected to improve disease monitoring and help inform risk of progression.


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