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Postdoc in Yeast Metabolic Engineering at Technical University of Denmark

Technical University of Denmark is delighted to offer a postdoctoral fellowship position in biochemistry. This position is available for 5 years. Applications should be sent before July 03, 2019.

Applications are invited for 2.5-year postdoctoral fellowship in the field of metabolic engineering and synthetic biology. The position is available as soon as possible. The position will be a part of Horizon 2020 European international project SHIKIFACTORY100 (http://shikifactory100.eu). SHIKIFACTORY100 aims towards the production of a universe of more than 100 high-added value compounds from the shikimate pathway through the development of an optimized shikimate chassis and implementation of novel biosynthetic routes exploring enzyme promiscuity to introduce new pathways for the production of known and newly designed compounds.

Microbial production of complex molecules is a well-established process for industrial compounds naturally produced by the hosts or for known compounds with fully characterized biosynthetic pathways. The shikimate pathway links metabolism of carbohydrates to biosynthesis of aromatic compounds. This pathway holds a very significant commercial interest, with many compounds associated with multi-million euros global market pools. The postdoctoral researcher will develop genetically engineered yeast for improving the shikimate chassis by using the modelling predictions and intracellular metabolome analysis. The candidate will use state-of-the-art methods for metabolic engineering and synthetic biology to create and improve yeast cell factories. Moreover, the candidate will optimize the fermentation process in controlled bioreactors and assist SHIKIFACTORY100 consortium partners with process scale-up. Responsibilities include, but are not limited to: The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union. The position is for 2,5 years.

Further information may be obtained from Irina Borodina, tel: +45 4525 8020, e-mail: irbo@biosustain. dtu. dk You can read more about the center on www. biosustain. dtu. dk Application procedure We must have your online application by the 3 July 2019. Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply online”, fill out the online application form, and attach all your materials in English in one PDF file.

All interested candidates irrespective of age, gender, race, religion or ethnic background are encouraged to apply.

The Novo Nordisk Foundation Center for Biosustainability is an international research center at the Technical University of Denmark funded by a grant from the Novo Nordisk Foundation. The center conducts research in metabolic engineering of cell factories, in silico systems biology, metagenomics and plant biochemistry with the purpose of developing new processes and technologies that can support a more sustainable bio-based production of valuable chemicals in the future. The Center brings together some of the world’s leading researchers in the field and will possess the advanced equipment and facilities required for achieving its ambitious research goals. Impact on society by innovation has a high priority and the Center collaborates worldwide with biotech companies and chemical industries to facilitate the dissemination and exploitation of its results. Additional information can be found at www.biosustain.dtu.dk DTU is a technical university providing internationally leading research, education, innovation and scientific advice. Our staff of 6,000 advance science and technology to create innovative solutions that meet the demands of society, and our 11,200 students are being educated to address the technological challenges of the future. DTU is an independent university collaborating globally with business, industry, government and public agencies.

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