Postdoctoral Researcher in Chemometrics and Data Mining

University of Amsterdam has an opening postdoctoral associate position in biodiversity. The initial contract for this position is two years and posible to extend. The deadline for applying is February 10, 2019.

Are you an analytical chemist interested in chemometrics and data mining? Then this might be the job for you. We are looking for an enthusiastic team player at the postdoctoral level to join a team working on unraveling the influence of photodegradation on chemical substances and materials.

TheInstitute for Biodiversity and Ecosystem Dynamics (IBED)is one of eight research institutes within the Faculty of Scienceat the University of Amsterdam (UvA). Our scientific work aims at a better understanding of the dynamics of ecosystems at all relevant levels, from genes to ecosystems, using a truly multi-disciplinary approach,based on both experimental and theoretical research. We want to unravel how ecosystems function in all their complexityand how they change due to natural processes and human activities.

Many organic compounds change under the influence of light. This can be beneficial, e.g. in water purification, but also undesirable, e.g.when cultural-heritage objects fade, affecting their esthetical value, or food ingredients degrade or toxic components are formed. Studying photodegradation is challenging, especially if the original composition is a complex mixture.

Within the TooCOLD project (Toolbox for studying the Chemistry of Light-induced Degradation), a system will be developed to study degradation of mixture components under the influence of light. Complex mixtures will be separated using (2D) LC techniques. The isolated components will be characterized by MS and trapped in an exposure cell for (surface-enhanced) resonance Raman Spectroscopy (RS). Next, these isolated components will be degraded by light using lasers or LEDs, which can be monitored by RS and separated by LC-hrMS in order to understand the degradation mechanisms.

For this project a position is available for a 3y postdoctoral researcher (f/m). The focus will beon workflow development for data acquisition, analysis and interpretation.

Multivariate resolution methods have been proposed to overcome fundamental challenges that occur during multidimensional chromatography analyses. Methods like generalized rank annihilation, parallel factor analysis, and curve resolution-alternating least squares have been applied for resolution, identification, and quantification of target compounds

Recent developments in mass spectrometry offer a tremendous increase in mass resolution that allow identification of unknown substances. Thus, a 'non-target' approach has emanated where hundreds to thousands of chemicals without references are screened simultaneously. This requires smart workflows that combine different software tools.

The TooCOLD project will be carried out within a collaboration of the Laserlab of the VU and the UvA Institute for Biodiversity and Ecosystem Dynamics (IBED). Other partners are Unilever, the van Gogh museum, the Cultural Heritage Agency of the Netherlands, PWN Technologies, KWR Watercycle Research Institute and Da Vinci Laboratory Solutions.

The starting date of the position on offer is flexible. You may start between May 2019 and September 2019, though we prefer an early start. The appointment is full-time (38 hours per week). Initially, we will appoint you on a temporary basis for one year. We offer you an extension of two years if we assess your performance positive. Your full-time gross monthly salary will range from 2,709 to 4,274 (salary scale 10), depending on your number of years of relevant experience. Your annual salary will be supplemented with 8% holiday allowance and 8,3% end-of-year bonus. The Collective Labour Agreement of Dutch Universitiesis applicable.

The UvA is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. We value a spirit of enquiry and endurance, provide the space to keep asking questions and cherish a diverse atmosphere of curiosity and creativity.

You may apply no later than 10 February 2019 using the link below. Please add vacancy number 19-020in the subject field of your letter.

Interviews are planned at the end of March/ early April. #LI-DNP


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