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PhD Scholarship in H2020 Eid Staccatto Differentiation of Stem Cells in 3D

Applicants are invited to apply for a PhD position in transplantation at KTH Royal Institute of Technology, Sweden. This position is available for two years. The deadline for applying is February 01, 2019.

KTH Royal Institute of Technology in Stockholm has grown to become one of Europe's leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden's largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy.

A call for 11 PhD positions (Early Stage Researchers [ESRs]) is open within the context of the recently granted European Industrial Doctorate project STACCATO – European Industrial Doctorate for enhancing upstream biopharmaceutical manufacturing process development through single cell analysis. STACCATO has been specifically designed to strengthen Europe's innovation capacity and leadership in biopharmaceutical manufacturing science by providing world-class intersectoral training to 11 Early Stage Researchers (ESRs) and creating and applying pioneering manufacturing process development approaches for biopharmaceuticals. All recruited researchers will spend at least 18 months of their time at industry partners. The successful candidates will profit of an international scientific network of high profile industry and academic partners. All fellows will benefit from intersectorial secondments, individual and networkwide training modules, including transferable skills courses. For further information please go to www.staccato-eid.eu.

The main goal within this project is to use stem cell differentiation to develop cellular therapies for diabetes. Silk proteins have a unique propensity to assemble their chains in an ingenious way so that a material with favourable properties is formed. The research group of Hedhammar has recently developed a method for facile, efficient and quick integration of cells into 3D culture by the assembly of silk into a network of microfibers mimicking the natural extracellular matrix. The recombinant silk protein used for this procedure is functionalized with a cell adhesion motif from the extracellular matrix protein fibronectin, thereby supporting 3D culture of also more sensitive cells. Within this project, the silk assmebly method will be used to create defined microenvironments for efficient and controlled differentiation of stem cells into pancreatic progenitors suitable for drug screening and transplantation purposes.

In order to succeed as an doctoral student at KTH you need to be goal oriented and persevering in your work.

Only those who are or have been admitted to third-cycle studies may be employed as a doctoral student. The term of the initial contract may not exceed one year and may thereafter be extended. Doctoral students may engage in teaching, research, and administration corresponding to a maximum of 20 % of a full-time position.

Apply for the position and admission through KTH’s recruitment system. It is the applicant's responsibility to ensure that the application is complete in accordance with the instructions in the advertisement.

Applications must be received at the last closing date at midnight, CET/CEST (Central European Time/entral European Summer Time).


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