PhD Scholarship in Computational Biophysics at KTH Royal Institute of Technology

A PhD scholarship is available at KTH Royal Institute of Technology. The funds for this position are available for two years. Eligible candidates should submit the applications before December 31, 2018.

KTH Royal Institute of Technology in Stockholm has grown to become one of Europe's leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden's largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy.

Membrane proteins, such as ion channels, enable cells to communicate with the outside world and are important pharmacological targets. The study of their function can be hampered by limitations in the experimental setups, making computer simulations a complementary tool of choice to investigate the details of their mechanics.

However, ion channel gating and allosteric regulation involves conformational changes occurring over time scales that are typically longer than the ones that can be directly observed using MD simulations. The project thus involves developing protocols that allow to sample these conformational changes using enhanced sampling techniques, by taking advantage of what is already known about the process (via interpretation of experimental results and/or long time-scale simulations). In a second step, the simulation output will be analyzed and interpreted.

The work in the group is highly international and cross-disciplinary. You will be a member of a research team with high-paced work, and the project includes collaborations with our international partner groups in the US.

In order to succeed as an doctoral student at KTH you need to be goal oriented and persevering in your work.

Only those who are or have been admitted to third-cycle studies may be employed as a doctoral student. The term of the initial contract may not exceed one year and may thereafter be extended. Doctoral students may engage in teaching, research, and administration corresponding to a maximum of 20 % of a full-time position.

Apply for the position and admission through KTH’s recruitment system. It is the applicant's responsibility to ensure that the application is complete in accordance with the instructions in the advertisement.

Applications must be received at the last closing date at midnight, CET/CEST (Central European Time/entral European Summer Time).


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