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Postdoctoral Research Assistant at University of Cambridge

University of Cambridge, UK is offering postdoc position in molecular biology. The initial contract for this position is 2 years. Eligible candidates should submit the applications before December 07, 2018.

Applications are invited for three Research Assistant/Associate positions (Postdoctoral scientists) to work in the research group of Professor Steve Jackson at the Gurdon Institute, University of Cambridge, https://www.stevejacksonlab.org/.

DNA in our cells is frequently subject to a wide array of molecularly-distinct forms of damage. To cope with this, life has evolved multiple DNA repair and associated processes, collectively termed the DNA-damage response (DDR). While considerable progress has been made in identifying DDR components and their regulators, much remains to be learned about how they operate and are controlled.

Building on successful recent work in our laboratory (see below), the research projects will be based on the experimental concepts of genetic enhancement and suppression (aka. synthetic lethality and synthetic viability, respectively). With assistance from a dedicated, experienced Research Assistant, each post-holder will carry out genome-wide and focused genetic screens in mammalian cells via state-of-the-art CRISPR-Cas9 approaches.

The work will be multi-disciplinary, combining recently-established genome engineering and genetic screening approaches in human or mouse cells with next-generation sequencing, bioinformatics, cell biology, molecular biology and biochemistry.

Candidates are expected to be independent and highly motivated and should have a PhD in cell or molecular biology, genetics, biochemistry or other related subject, or be close to completion of their degree. Candidates should have strong mammalian DDR experience and/or experience in CRISPR-Cas9 genome engineering. Applicants should have excellent written and spoken English communication skills and should be able to work both independently and as part of a team.

The positions offer a competitive salary and enjoy the diverse, vibrant and highly supportive research environment of the Gurdon Institute and the University of Cambridge.

Limited funding: The funds for this post are available for 2 years in the first instance.

The Gurdon Institute is committed to equality and diversity in the workplace, for more information go to: https://www.gurdon.cam.ac.uk/about/athenaswan.


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