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Postdoc Position at University of Cambridge

Applicants are invited to apply for a postdoctoral researcher position in biotechnology at University of Cambridge. Successful candidate will have funding to work and study for two years in UK. Applicants should apply before November 28, 2018.

The Buss laboratory at the Cambridge Institute for Medical Research is looking to recruit a post-doctoral Research Associate, funded by the Biotechnology and Biological Sciences Research Council, to study the kinetic properties of myosin motor proteins using a range of biophysical approaches. The work of the Buss lab aims to establish how different classes of myosin motors have fine-tuned their motor mechanics to full-fill their specialised cellular functions.

This project will focus on defining the select adaptations of different classes of myosin motors in cytokine secretion. The researcher will focus on characterising the kinetic properties and regulation of myosin motors that play a role in cytokine secretion.

We are seeking a highly motivated Biochemist/Biophysicist with expertise in protein expression in eukaryotic expression systems and a range of biophysical techniques including micro scale thermophoresis (MST), dynamic light scattering (DLS), FRET assays, TIRF and optical tweezers. Experience with establishing and performing in vitro fluorescent microscopy experiments to test established and novel small molecule inhibitors is essential. A background in molecular motors and the use of single molecule imaging and mechanical experiments is also desirable.

The Cambridge Institute for Medical Research (CIMR) forms part of the University of Cambridge Clinical School and is based in the Wellcome Trust/MRC Building on the Cambridge Biomedical Campus. The Institute provides modern laboratory accommodation and state of the art research facilities http://www.cimr.cam.ac.uk . As part of the University of Cambridge Clinical School, each Principal Investigator is affiliated to a home department which includes Clinical Biochemistry, Haematology, Medicine, Medical Genetics, Clinical Neurosciences and Pathology.

Fixed-term: The funds for this post are available for 1 year in the first instance. Interviews will be held in December 2018 and ideally the contract should start on 1st January 2019.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

For informal enquiries please contact Professor Folma Buss on fb207@cam.ac.uk For any information regarding the application process, please contact Susan Brasher on sib25@cam.ac.uk


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