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PhD Scholarship Position in Medical Science Neural Predictors of Human Cardiovascular Disease

Applicants are invited to apply for a PhD position in medical sciences at University of Gothenburg. The funds for this position are available for 4 years. Eligible candidates should submit the applications before November 28, 2018.

The Department of Clinical Neuroscience is located at the Institute of Neuroscience and Physiology at the Faculty of Health Care Sciences at Sahlgrenska Academy, University of Gothenburg. At the Department research is conducted covering the following areas; neurology, neurosurgery, clinical neurophysiology, ophthalmology, rehabilitation medicine and experimental neuroscience in close collaboration with Sahlgrenska University Hospital. We are responsible for courses on the degree programmes for future physicians, biomedical analysts, occupational therapists, physiotherapists and speech & language pathologists. We also offer contract education and have collaboration with the Department of Neuro Health Care at the Sahlgrenska University Hospital. At the Department there are about twenty research groups.

General information about third-cycle studies: The PhD education in Medical Science corresponds to studies of 240 credits in total. The studies are equivalent to four year full-time and lead to a Degree of Doctor. The studies comprisecarrying out a scientific project and completing at least 30 credits of courses at third-cycle level. The doctoral student must also write a scientific compilation thesis or monograph corresponding to at least 120 credits. For more information about third-cycle studies at Sahlgrenska Academy, see

https://medarbetarportalen.gu.se/sahlgrenskaakademin/forskarutbildning/?languageId=100001

Project: Hypertension has recently been established as the most important risk factor for total disease burden in the world. Intraneural recording of sympathetic nerve activity in man has provided detailed information about dynamic neurovascular control in health and disease, including the identification of individual response profiles elicited by arousal/stress which predict risk for developing hypertension. However, the complexity and invasiveness of intraneural recording does not allow longitudinal investigation of large study groups.

The primary aim of this project is to evaluate brain response patterns that correlate with the peripheral sympathetic responses to arousal, using magneto- and electro-encephalography (MEG and EEG) in conjunction with peripheral nerve recording. Results will be compared to structural and functional magnetic resonance (MR) data collected in a separate session from the same subjects (who are all healthy volunteers) to allow a better understanding of brain processing of sympathetic homeostasis . A long term aim of this projectis to identify putative non-invasive surrogate variables to be used in future large cohort studies aimed at reducing cardiovascular risk.

The research group has extensive experience in the microneurography field, as well as in clinical neurophysiology methods in general (including EEG), and a growing experience regarding MEG. A physicist (senior lecturer Justin Schneiderman) with specific MEG focus will act as co-supervisor, as will a trained microneurographer (postdoc LindaLundblad). To be eligible for third-cycle studies, the applicant must meet both the general and specific entry requirements.

A person meets the general entry requirements for third-cycle studiesif he or she:

1. has been awarded a second-cycle qualification 2. has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second-cycle, or 3. has acquired substantially equivalent knowledge in some other way in Sweden or abroad A person meets thespecific entry requirements for third-cycle studiesif he or she: has successfully completed the English B/6 course or is considered to have acquired equivalent knowledge through previous studies

In selecting between applicants who meet the general and specific entry requirements, their ability to benefit from third-cycle studies shall be taken into account. The assessment shall attach particular importance to documented qualifications for:

– specific knowledge and skills within the subject area and related research fields – experience of scientific theory and relevant research methodology – scientific analysis and presentation verified through thesis, degree project, scientific journals or the like. Documented experience from experimental physiology studies on humans is valued, as is experience from analysis of physiological data in general. Experience in the field of human nervrecording is of specific value.

Time limited employment (temporary),4 years.Extent:100%. Location: Sahlgrenska Academy, Institute of Neuroscience and Physiology, Department of Clinical Neuroscience. First day of employment: as agreed.

Regulations for employment of doctoral students are given in SFS 1998:80.Only those who are admitted to third-cycle studies may be appointed to doctoral studentships. Those appointed to doctoral studentships shall primarily devote themselves to their studies. They may, however, work to a limited extent with educational tasks, research and administration according to the regulations.

The initial appointment may apply for no longer than one year. An appointment may be renewed for no more than two years at a time. The total employment period may not exceed the time corresponding to full-time third-cycle studies for four years.

Salaries for doctoral students are regulated in a local agreement at the University.

For more information about the project please contactthe principalsupervisor,

Mikael Elam, Professor, mikael.elam@gu.se Union representatives at the University of Gothenburg:

http://www.gu.se/english/about_the_university/job-opportunities/union-representatives In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. Attach verified copies of your education and English proficiency proving your eligibility. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application.

The University of Gothenburg promotes equal opportunities, equality and diversity.

Salaries for doctoral students are regulated in a local agreement at the University.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.


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