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PhD Scholarship at University of Ghent

University of Ghent is pleased to invite applicants to apply for a PhD position in proteomics. This position is closed on November 25, 2018.

The ELEVATE project "EarLy dEtection of cerVical cAncer in hard-to-reach populations of women through portable and point-of-care HPV Testing" aims to improve the adequacy and coverage of cervical cancer screening. The ELEVATE team will develop a new technology for a point-of-care, portable, low-cost, user-friendly, HPV testing device, to be used in "hard-to-reach” populations in Europe and Latin America. This project brings together a multidisciplinary team of physicists, electronic engineers, biochemists, biologists and medical practitioners to solve fundamental problems associated with the development of such device.

The PhD project aims at the development of a proteomic electrochemical sensor for the detection of two disease-specific biomarkers, for a reliable identification of HPV transforming infections associated with cancer progression. Electrochemical sensors are known to be powerful tools for the fast detection of biomolecules in fluids, and are becoming of critical importance in, among other application fields, clinical analysis and diagnostics. In addition, the attachment of bioactive proteins to surfaces underpins the development of novel, rapid and inexpensive biosensors that can improve and/or complement the current clinical care settings.

The final platform will include chemical and biosensors integrated into a microfluidic system for the detection of relevant analytes in HPV. Sensors will be made of electrochemical cells on inexpensive and robust substrates, fabricated mainly through screen-printing technologies. Bio-functionalisation will be performed for the selective detection of the biomarkers.

The project is funded by the European Commission and will be performed in close collaboration between Ghent University research groups and other European and Latin American academic and industrial researchers. The selected candidate will have the unique opportunity to be involved in the early stage development of a novel PoC tool for cervical cancer diagnostic.

Please send your CV, containing possible publications, preferably names and contact information of 1 or 2 referees, and a motivation letter to Prof. Jan Vanfleteren (Jan.Vanfleteren@ugent.be), before 25/11/2018. Early application is encouraged as the applications are processed upon reception.


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