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Postdoc Position Single Molecule Imaging of Liquid Droplet Formation in Neurodegenerative Disease

University of Cambridge has an opening postdoctoral fellowship position in mathematics. Potential candidates should apply before November 22, 2018.

Fixed-term: The funds for this post are available until December 31, 2020 in the first instance.

A postdoctoral position is available in the group of Professor David Klenerman in the Department of Chemistry at Cambridge University. The project is to use fluorescence imaging methods to follow the reversible phase separation of liquid droplets of proteins with intrinsically disordered domains, a process associated with the development of neurodegenerative diseases such as such as familial amyotrophic lateral sclerosis (see Qamar et al., 2018, Cell 173, 720734 ) and characterise the nature of the droplets formed. Experiments will be performed in vitro and then extended to cells.

Applicants should have a PhD (or equivalent) in single molecule fluorescence, biophysics or super-resolution microscopy. Previous experience of imaging protein aggregates or cell imaging is desirable.

The position is available from January 1 st 2019.

Please ensure that you upload your Curriculum Vitae (CV), a covering letter and publications list in the upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.

Informal inquires can be addressed via email to Professor David Klenerman (dk10102@cam.ac.uk).


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