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Postdoc Position at University of Cambridge

A new postdoctoral researcher position in genomics is available at University of Cambridge. Candidates are welcome before November 25, 2018.

We are looking for a data analyst or computational biologist to join our multidisciplinary team (https://www.molecularinformatics.org) in the Cancer Research UK Cambridge Centre Early Detection Programme (https://www.earlydetectioncambridge.org.uk). The successful candidate will work closely with experimental researchers, clinical colleagues and collaborating computational groups. Specifically, the role will involve analysis of genomic sequencing data and the development of new analysis workflows that will facilitate clinical/translational testing of cancer early detection assays. This key role in our group will require extensive quantitative data analysis experience, preferably including high throughput genomic data analysis. Advanced programming skills are a must, in addition to experience of high-performance computer environments, schedulers and pipelining tools. Experience of working in multidisciplinary teams and good communication skills will be needed to ensure effective cross-working with colleagues and collaborators in order to develop useful analysis workflows for clinical/translational research.

Cancer survival rates are highest when diagnosed at an early stage, therefore we are developing sensitive, specific and minimally invasive tests that could inform the early detection and stratification of urological cancers. Our projects build on the results of large-scale molecular profiling studies [1] to implement targeted high-sensitivity genomic analyses of circulating tumour DNA (ctDNA) in liquid biopsies [2]. Molecular markers include recurrent genomic alterations [1,3] and epigenetic changes [4-5] that are specific features of early stage cancers. These studies generate large amounts of genome sequencing data and require bespoke analysis methods to identify rare events with high accuracy and recall.

There will be considerable scope for personal development in this post, through access to training courses, collaborative working with leading groups in the field and mentoring support. Effective coordination with colleagues and collaborators will be key in this role, as will innovative thinking to ensure the maximum impact in these multidisciplinary projects.

For informal inquiries or more information about the role please contact Dr Charlie Massie on cem45@cam.ac.uk.

Fixed-term: The funds for this post are available until 30 April 2021 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a security check. This appointment also requires a Research Passport application.

The closing date is 25th November 2018, with interviews to be confirmed.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.


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