PhD Scholarship in Physical Chemistry Molecular Spectroscopy and Biophysics

Applications are invited for a PhD position in medicinal chemistry to join University of Gothenburg. The funds for this position are available for 5 years. The deadline to apply is October 21, 2018.

Research and graduate education at the department of chemistry and molecular biology comprises a wide scientific field from the atomic and molecular levels all the way through cells to intact organisms. Much of the phenomena studied here impact on our natural environment and living systems. We participate in undergraduate programs in chemistry, molecular biology, medicinal chemistry, biology, marine sciences, and pharmacy.

A third cycle education at our department will lead to a Ph.D. in Natural sciences, or Natural sciences with a specialisation in Chemistry, Biology or Biophysics. Ph.D. studies comprises four years at the post graduate level. The time period can be extended to 5 years in total through teaching and/or other departmental duties.

The position is opened in the newly established laboratory of Dr. Micha Maj and in close collaboration with the group of Prof. Sebastian Westenhoff. The successful candidate will be working in the field of two-dimensional infrared (2D-IR) spectroscopy of proteins, with a particular focus on studying mechanisms that govern the formation of amyloid fibrils. The deposition of amyloid aggregates in organs and tissues is linked to the development of various degenerative diseases such as type II diabetes and Alzheimer's disease. The aggregation process involves formation of transient and potentially toxic species that cannot be detected by the majority of structural biology techniques. 2D-IR spectroscopy, on the other hand, holds great promise for elucidating the aggregation mechanism by resolving such previously undetected intermediates.

The study will combine a variety of biomolecular, analytical, and computational techniques. The candidate will learn how to operate femtosecond laser systems, synthesize and purify peptide and protein samples, process and analyse experimental data, and write scientific publications.

1. has been awarded a second-cycle qualification, 2. has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second-cycle, or 3. has acquired substantially equivalent knowledge in some other way in Sweden or abroad. To meet the specific entry requirements for third-cycle studies, applicants must: (i) have a second-cycle (advanced-level) degree in a relevant* subject area in the natural sciences, or (ii) have completed studies for at least 60 higher education credits at a second-cycle level in relevant subject areas in the natural sciences, or (iii) have completed a corresponding programme of relevance to the planned third-cycle programme, in Sweden or in another country, or have equivalent qualifications. The specific entry requirements also include an acceptable command of spoken and written English. Guidelines for assessing English proficiency may include a minimum score of 550 on the TOEFL test (or 213 on the TOEFL-CBT, or 79 on the TOEFL-iBT).

Regulations for the evaluation of qualifications for education on a doctoral level are given in SFS 1998:80.

Type of employment: Fixed-term employment, four years full time

Extent: 100 % Location: Department of Chemistry and Molecular Biology, Gothenburg First day of employment: according to agreement Regulations for the evaluation of qualifications for education on a doctoral level are given in SFS 1998:80.

A new employment as a PhD student applies for a maximum of one year. The Appointment may be prolonged for up to two years at a time. The total employment period may not be longer than the equivalent of four years of full time time doctoral studies.

-Cover Letter describing your vision of doctoral studies and your future after graduation – clearly state your interests and expectations and how they fit the advertised position-CV including scientific publications

-Copy of graduation certificate -Two references (name, telephone no, relation) -Academic transcript of grades from both your undergraduate and M.Sc studies.

Please contact Dr Michal Maj: , for specific questions regarding the position.

Questions regarding the third-cycle education: Martin Billeter, Director of third cycle education, +46(0) 31-786 3925, Questions regarding the employment: Union representatives at the University of Gothenburg:

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application.

The University of Gothenburg promotes equal opportunities, equality and diversity.

Salaries for doctoral students are regulated in a local agreement at the University.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.


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