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PhD Scholarship in Mathematical Statistics Specializing in Spatial Statistics in Molecular Biology

Stockholm University, Sweden is offering PhD position in biochemistry. The initial contract for this position is four years. The deadline for applying is November 05, 2018.

General description:

This a pair-doctoral project where one of the PhD students is linked to the Department of Mathematics and has his/her main supervisor there. The other doctoral student is linked to the Department of Biochemistry and Biophysics and has his/her main supervisor there. The two main supervisors are deputy supervisors of each other’s PhD students. Project description

Nearly 40 years ago, DNA was sequenced for the first time. Since then, DNA sequencing has undergone continuous development, passing through three generations of sequencing technology. We are now entering the beginning of a new phase in which massively parallel sequencing is performed directly in the cell. Mats Nilsson's lab has pioneered a technique called in situ sequencing that detects large numbers of gene transcripts in cells in tissue sections in a targeted way. His lab works with two data sets: one concerns mapping neurons in mouse brains, the other one concerns generating data from breast cancer tumors. The general goal of the project is to answer the question "do some cells/molecules end up in certain spatial location in relation to each other?" These biological issues pose challenges concerning both statistical data analysis and statistical inference. The methods of spatial statistics are key. An example of such a method is t-Distributed Stochastic Neighbour Embedding (t-SNE) which has become widespread in the field of machine learning. The method uses classical divergence measure but there is a potential possibility to use other measures. Spatial statistics includes a variety of techniques of which many are still in their early development. There is hence a potential to develop new spatial analysis methods to answer biological questions.

The PhD student should have a deep understanding of statistical methods with documented programming skills, and should have enough understanding of biology to be able to discuss and work together with the PhD student at the Department of Biochemistry and Biophysics.

Qualification requirements

In order to meet the general entry requirements, the applicant must have completed a second-cycle degree, completed courses equivalent to at least 240 higher education credits, of which 60 credits must be in the second cycle, or have otherwise acquired equivalent knowledge in Sweden or elsewhere.

For information on special eligibility requirements, please see: eligibility and selection.

The qualification requirements must be met by the deadline for applications.

Selection

The primary assessment criteria in appointing a PhD student is the capacity to complete the research training. The selection of candidates is based upon the earlier studies, grades, quality of theses, references, the written application and, for a smaller group of selected candidates, interviews.

Admission Regulations for Doctoral Studies at Stockholm University are available at:www.su.se/rules.

Only a person who will be or has already been admitted to a third-cycle programme may be appointed to a doctoral studentship.

The term of the initial contract may not exceed one year. The employment may be extended for a maximum of two years at a time. However, the total period of employment may not exceed the equivalent of four years of full-time study.

Doctoral students should primarily devote themselves to their own education, but may engage in teaching, research, and administration corresponding to a maximum of 20 % of a full-time position.

Please note that admission decisions cannot be appealed.

Stockholm University strives to be a workplace free from discrimination and with equal opportunities for all.

Contact

For more information, please contactsupervisor Joanna Tyrcha, joanna@math.su.se ordirector of PhD studies Mia Deijfen, mia@math.su.se.

Application

Apply for the PhD student position at Stockholm University’s recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the advertisement, and that it is submitted before the deadline.

Please include the following information with your application

and, in addition, please include the following documents(in pdf-format)


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