Research Associate/Senior Research Associate - Cryo-EM (Fixed Term)

University Of Cambridge is offering postdoc position. All students regardless of citizenship are eligible to apply. Applications are invited up to September 23, 2018.

We seek a highly skilled and experienced researcher to join the group of Professor Alan Warren at the Cambridge Institute for Medical Research on the Cambridge Biomedical Campus.

The Warren lab uses a multidisciplinary approach including genetics, biochemistry and structural studies (Zyryanova et al. Science 2018; Warren AJ. Adv Biol Regul 2018; Weis et al. Nature Struct Biol 2015; Wong et al. Blood 2011; Barlow et al. Nat Med. 2010; Finch et al. Genes Dev 2011; Menne et al. Nat Genet 2007) to investigate mechanisms of eukaryotic ribosome maturation and to understand how corruption of this process causes bone marrow failure and cancer predisposition. We use a number of models including Dictyostelium, yeast, Drosophila and mice and make extensive use of cryo-electron microscopy. We enjoy a collaboration with the group of Rob Kay at the MRC Laboratory of Molecular Biology which has great strengths in the study of Dictyostelium (Paschke et al. PLoS One 2018).

We seek someone who will make a significant contribution to our research. They will lead their own experiments and work closely with other members of the group to bring interdisciplinary projects to publication. They will have a particular focus on Dictyostelium but will have the expertise to be able to contribute more widely, for instance to the development of models using other organisms. They will be able to provide advice and training to other lab members on a range of topics.

The candidate will have a PhD in a relevant area of the biological sciences. They will have extensive cell biology experience. Experience of working with Dictyostelium, in particular the generation of Dictyostelium mutant strains and culture of Dictyostelium cells, is essential. Previous involvement in research on ribosome biogenesis would be highly advantageous. They will have at least three first author publications.

Appointment to Senior Research Associate is subject to approval by the Faculty Board of Clinical Medicine.

Fixed-term: The funds for this post are available until 30 September 2019 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the ‘Apply’ button below. This will route you to the University’s Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Informal enquiries are welcomed and should be directed to Professor Warren at

Interviews are expected to be held in the week commencing 1st October 2018.

Please quote reference SB16717 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.


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