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Research Associate Bioinformatician

Applicants are invited to apply for a postdoc position at Imperial College London. Citizens of any country are eligible to apply. Applicants should apply before September 17, 2018.

This computational biologist / bioinformatician post is part of the Cardiovascular Genetics and Genomics research team, which spans the National Heart and Lung Institute at Imperial College London, the Cardiovascular Research Centre at Royal Brompton Hospital and the MRC London Institute of Medical Sciences (LMS). The group's research is aimed at understanding the genetic basis of cardiovascular disease, and particularly inherited heart diseases. Principal Investigators in the team include James Ware, Paul Barton, Declan O'Regan and Stuart Cook. The post-holder will work under the supervision of Dr James Ware. For more information on current research directions, see Dr Ware's website at http://www.imperial.ac.uk/people/j.ware or the group page at www.cvgenetics.org.

The post-holder will be embedded in a well-established bioinformatics team, and will be responsible for a new project applying integrative genomic approaches to understand the role of non-coding genomic elements in heart disease with a particular focus on inherited cardiomyopathies. They will lead computational analyses of genomic data from humans and model systems, including the genome, and cardiac transcriptome, translatome, and epigenome, and will leverage these to understand human disease and improve clinical genome interpretation. This is an excellent opportunity for a dynamic and experienced bioinformatician with skills and knowledge in statistical data analysis to contribute to a cutting-edge new project investigating the role of non-coding genetic elements in inherited heart disease. You will be responsible for leading computational analyses integrating genomic data from human and model systems. You will leverage aggregated datasets from the genome, cardiac transcriptome, translatome, and epigenome, to understand human disease and improve clinical genome interpretation. In addition, you will have the opportunity to contribute to other genomics research programs within the group.

You will need to hold a PhD and have prior experience in both Bioinformatics and statistical data analysis. Ideally, you will have experience analysing high-throughput sequencing data and knowledge of human cardiovascular genetics. You will have scripting skills in R/Perl/Python and shell, and will have experience working in a high-performance computing environment. You will have the ability to work independently and have experience of project leadership. You will also be able to adapt quickly as part of a cross-disceplinary team in a rapidly changing environment.

If you have any queries regarding this post please contact: James Ware – j.ware@imperial.ac.uk

If you have any queries regarding the recruitment process please contact: Daisy Alasya-Wade – d.alasya-wade@imperial.ac.uk

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