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Postdoctor within Translational Cancer Research at Lund University

Applicants are invited to apply for a postdoctoral position in nanotechnology at Lund University, Sweden. Potential candidates should apply before October 04, 2018.

Lund University was founded in 1666 and is repeatedly ranked among the world's top 100 universities. The University has 40 000 students and 7 400 staff based in Lund, Helsingborg and Malm. We are united in our efforts to understand, explain and improve our world and the human condition.

The Faculty of Medicine is a part of Lund University, and is responsible for education and research within medicine and healthcare. Our academic programs are closely linked with the healthcare system and are firmly anchored in the faculty's strong research tradition. Our research spans a broad field within experimental preclinical research, near-patient clinical research and health sciences research. The Faculty of Medicine, with its 1,800 employees and 2,700 students in Lund and Malm, is a knowledge-intensive meeting place for students, teachers and researchers from all over the world.

The Department of Laboratory Medicine is one of six departments at Lund University's Faculty of Medicine. We conduct leading research, both broad and specialised, within the field of laboratory medicine, focusing on the onset of disease and how we can improve diagnostics and treatment for patients. Some of our strongest areas with world-class research deal with cancer, genetics and blood.

The division of Translational Cancer Research and the laboratory of Chris Madsen is looking to hire a post doc. The main focus of the group, is to try to understand how cancer spreads through the body (a process called metastasis) as this is responsible for over 90% of cancer-related patient deaths. Metastasis is strongly influenced by the physical and chemical properties of the tumour microenvironment. The group studies how cancer cells move through this remodeled environment and aim at targeting intrinsic mechanisms of cancer cell motility as well as the mechanisms underlying the tissue remodeling. Our group use advanced microscopy to understand metastatic progression and tissue remodeling i.e. using 2-photon microscopy, multispectral optoacoustic tomography and ultrasound. We take a multidisciplinary, integrative approach to perform high quality translational cancer research with collaborative partners world-wide. Work duties

The post doc will undertake work to validate new regulators of mechanotransduction and mechanobiology in cancer, vascular disease and in mesenchymal stromal cell differentiation. The project will cover both in vitro and in vivo experimentation and have three major aims: 1) to characterize the molecular mechanism by which a new regulator of mechanotransduction is controlled 2) to validate the findings in vivo using animal models of cancer and 3) to validate the potential in regenerative medicine and differentiation of stem cells. Moreover, the postdoc will co-supervise and be responsible for the practical training of students in our group, and be in charge of the practical training and guidance of all work related to stromal and mesenchymal differentiation. The postdoc will also actively collaborate with scientist outside the field of biology incl. nanotechnology and physics.
- A PhD in Natural Science (physical or life science) or Medicine
- Knowledge on stromal cell purification from in vivo models using FACS sorting Personal characteristics

The postdoc applicant needs to be a motivated individual with high level of independence. The individual must be confident with a high degree of leadership responsibility and future leadership training. The applicant must be fluent in English, both in written and oral presentation. We therefore are very pleased if the application is submitted in English. Emphasis will be held on personal suitability.


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