Postdoctor in Translational Cancer Research at Lund University

Lund University is pleased to invite applicants to apply for a new opening postdoctoral associate position in nanotechnology. Applicants should apply before October 03, 2018.

Lund University was founded in 1666 and is repeatedly ranked among the world's top 100 universities. The University has 40 000 students and 7 400 staff based in Lund, Helsingborg and Malm. We are united in our efforts to understand, explain and improve our world and the human condition.

The Faculty of Medicine is a part of Lund University, and is responsible for education and research within medicine and healthcare. Our academic programs are closely linked with the healthcare system and are firmly anchored in the faculty's strong research tradition. Our research spans a broad field within experimental preclinical research, near-patient clinical research and health sciences research. The Faculty of Medicine, with its 1,800 employees and 2,700 students in Lund and Malm, is a knowledge-intensive meeting place for students, teachers and researchers from all over the world.

The Department of Laboratory Medicine is one of six departments at Lund University's Faculty of Medicine. We conduct leading research, both broad and specialised, within the field of laboratory medicine, focusing on the onset of disease and how we can improve diagnostics and treatment for patients. Some of our strongest areas with world-class research deal with cancer, genetics and blood.

The division of Translational Cancer Research and the laboratory of Chris Madsen is looking to hire a post doc. The main focus of the group, is to try to understand how cancer spreads through the body (a process called metastasis) as this is responsible for over 90% of cancer-related patient deaths. Metastasis is strongly influenced by the physical and chemical properties of the tumour microenvironment. The group studies how cancer cells move through this remodeled environment and aim at targeting intrinsic mechanisms of cancer cell motility as well as the mechanisms underlying the tissue remodeling. Our group use advanced microscopy to understand metastatic progression and tissue remodeling i.e. using 2-photon microscopy, multispectral optoacoustic tomography and ultrasound. We take a multidisciplinary, integrative approach to perform high quality translational cancer research with collaborative partners world-wide. Work duties

The post doc will undertake work to validate a new anti-metastatic drug candidate in breast cancer. The project will cover both in vitro and in vivo experimentation and have two major aim: 1) peri-nuclear cytoskeletal re-organization during cell migration in confined environments and 2) peri-cellular matrix degradation during cancer cell migration and metastasis of breast cancer. The post doc will also help to develop specific matrix-degradation probes for the application of multispectral optoacoustic tomography (MSOT) imaging, a non-invasive whole animal imaging modality. This part will be in tight collaborations with other researchers of the group. Moreover, the postdoc will co-supervise and be responsible for the practical training of students in our group, and be in charge of the practical training and guidance of our fluorescence imaging platform. The postdoc will also actively collaborate with scientist outside the field of biology incl. nanotechnology and physics.
- A PhD in Natural Science (physical or life science) or Medicine
- Documented experience with work on the cytoskeletal network Personal characteristics

The postdoc applicant needs to be a motivated individual with high level of independence. The individual must be confident with a high degree of leadership responsibility and future leadership training. The applicant must be fluent in English, both in written and oral presentation. We therefore are very pleased if the application is submitted in English. Emphasis will be held on personal suitability.


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