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PhD Position in Decision-support in Perioperative Care

Eindhoven University of Technology is pleased to invite applicants to apply for a PhD position in signal processing. The funds for this position are available for 4 years. There is no application deadline for this position.

The ageing population and the increased incidence of chronic disease is imposing unparalleled financial and societal burden. There is an urgent need for a paradigm shift towards “precision medicine”: a tailored, personalized approach in medicine to improve patient care and quality of life, while reducing healthcare costs. Despite improvements in anesthesia and post-operative care, about 25% of patients undergoing surgery suffer from serious post-operative complications. Early identification of patients at risk is fundamental to enable effective prevention, improve patient safety, and permit optimal guidance of clinical decision making. This must be combined with unobtrusive, continuous patient monitoring at all levels of care to enable patient-specific decision support.

Prevention and timely intervention have been facilitated by the implementation of warning systems. However, current systems typically rely on sparse, non-real-time data sampled from the patient to calculate warning scores. These are mostly based on heuristic predictive models detecting deviations from population-averaged “normal” values. Thus, they have limited accuracy, they are not patient-specific, and they can only be used for long-term prognosis. A step towards more intelligent decision-making tools calls for real-time, patient-specific, quantitative analysis of a bio-signals in a dynamic, adaptive paradigm, able to incorporate domain knowledge and new measurements as they become available.

The BM/d lab is devoted to model-based quantitative analysis of medical images and bio-signals, with the goal of improving patient care and management. In the context of perioperative care, we focus on modeling and analysis of bio-signals, taking into account the full measurement chain, with the goal of improving diagnosis and prognosis, and enabling long-term monitoring. By model-based signal analysis we aim at extracting features that are related to the underlying physiology/pathology, facilitating clinical interpretability. Combination of model-based feature extraction with data-driven approaches, e.g. machine learning, for feature selection enables the development of effective risk prediction models to support clinical decision making. Exploiting the increasing availability of large clinical datasets, data-driven approaches offers an opportunity to unravel hidden aspects of the underlying complex physiology, which might be relevant for understanding the investigated process, yet not directly measurable.

In this context, we are seeking a highly motivated master graduate with knowledge and interest in medical data analytics, and with a strong background in model-based analysis of bio-signals. The position is available within the BM/d research lab, part of the Signal Processing Systems (SPS) group (Electrical Engineering department, TU/e), and it involves joint collaborations with the Stochastics group (Mathematics and Computer Science department, TU/e), and with clinical and industrial partners, including the Catherina Ziekenhuis Eindhoven and Philips, as part of the Eindhoven MedTech Innovation Center (e/MTIC).

We are looking for candidates that meet the following requirements:

- Affinity for working in an interdisciplinary and highly international environment.

- A full-time temporary appointment for a period of 4 years, with an intermediate evaluation after 9 months;

- A gross salary of (2.222) per month in the first year increasing up to (2.840) in the fourth year;

- Travel funding for presenting your work at the leading conferences.

- Support for your personal development and career planning including courses, summer schools, conference visits etc.;

- A broad package of fringe benefits (e.g. excellent technical infrastructure, child daycare, excellent sports facilities, extra holiday allowance [8%, May], and end-of-year bonus [8.3%, December]).

For more information about this position contact dr. ing. Simona Turco, e-mail: s.turco@tue.nl

More informationonemployment conditionscanbefound here: http://www.tue.nl/en/university/working-at-tue/working-conditions/. Application

If interested, please use ‘apply now’-button at the top of this page. You should upload the following: - Cover letter explaining your motivation and qualifications for the position, as well as your current experience with and understanding of the topic

- A copy or a link to your MSc thesis. If you have not completed it yet, please explain your current situation;

- List of courses taken at the Bachelor and Master level including marks;

- Names of at least two referees.

Please keep in mind; you can upload only 5 documents up to 2 MB each! The selection process with start in July 2018 and will continue until the position gets filled. The position is fully funded and immediately available. The successful candidates are expected to start ASAP.


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