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PhD Scholarship in Biology at Commissariat à lEnergie Atomique

Commissariat à lEnergie Atomique is pleased to invite applicants to apply for PhD scholarship in biology. This scholarship is available for all students around the world. The deadline for applying is March 31, 2015.

G Protein-Coupled Receptors (GPCRs) are membrane proteins involved in the communication between cells through circulating messengers (hormones, neurotransmitters) and also in sensing our environment (vision, smell, taste). They are essential to numerous physiological functions which are vital (cardiac, breathing,.) and behavioral (social and emotional relationships).

We have developed an original biosensor based on the fusion of GPCRs with an ion channel. Motions of the receptor induced by its activity (ligand binding, G protein activation) are translated by the ion channel into an electric current easily detectable by electrophysiological techniques. We have successfully used this technology to detect the cholesterol dependency of archetypal receptors and envision developing it to study artificial lipid compounds such as bisphenol A and other endocrine disruptors.

The task of the PhD student will consist in developing this technology by using different GPCRs and known and potential endocrine disruptors.

Benefits
The salary is 2043.54 € / month (gross income).

Application Requirements
- Excellent academic records.
- From Universities or Engineering Colleges with a Master degree (if French M2, grade B or higher) or equivalent.
- Experience or interest in membrane proteins, biochemistry, molecular biology or electrophysiology.
- The working language in the lab is English.

How to apply?
- In Feb.-March, candidates must apply through the dedicated website http://www-dsv.cea.fr/en/phd-program/irtelis-competitive-phd-recruitment and select the projects of interest. Thesis SL-DSV-15-0810.
- The pre-selected candidates will be interviewed by the CEA-Irtelis committee in Paris.
- The committee selects the final successful candidate

Scholarship Summary


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