Cancer Imaging PhD Scholarship

The University of Manchester is offering a PhD scholarship in Cancer Imaging. The deadline for applying this position is on January 30, 2015.

Imaging modalities such as Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) can be used to measure functional and structural features of tumours in cancer patients. Currently this is typically limited to whole tumour metrics due to the limitations of imaging modalities to measure, and complications of portraying, heterogeneous variations within tumours. Most tumours demonstrate heterogeneity, with this increasingly recognised as clinically important, as the regions of the tumour that are most therapy resistance or aggressive will have greatest influence on response to therapy and prognosis.

The PhD project will address this by aiming to develop novel methods for the identification of the degree of heterogeneity within tumours and the identification of areas of distinct function. The study will focus on PET data, which is particularly challenging due to limitations in image resolution and signal-to-noise but also aim to utilise complementary data from other modalities such as MRI. Specifically the developed methods will be incorporated within image reconstruction in order to avoid the misinterpretation of noise within the images as heterogeneity. It is envisaged that this will involve the development of spatiotemporal models of radiotracer distribution and the used of Bayesian statistical methods. The benefit of the developed methods will be evaluated using a combination of simulations, phantom and real clinical data.

The studentship provides full support for tuition fees, conference/travel allowance and annual minimum tax-free stipend of £ 19,000.

Due to commence October 2015, the project is open to UK/EU nationals only due to the nature of the funding. There is scope for the project to start earlier subject to the preference of the successful candidate.

Application Requirements
The PhD will provide training in a number of multi-disciplinary areas including biomedical imaging; mathematical and numerical methods within image reconstruction algorithms; medical physics in PET and MRI and cancer biology.

Research will be based at the Wolfson Molecular Imaging Centre (WMIC) a stimulating environment with opportunities to interact with a significant number of fellow early-career researchers and observe scan acquisitions.

We are seeking applicants with a background in an analytical related discipline such as mathematics, physics or engineering. It is expected that candidates would hold (or be due to obtain) a minimum upper-second class degree (or equivalent) in such an area. A Masters qualification and/or previous medical imaging experience would be an advantage.

How to apply?
Please direct applications in the following format to Dr Julian Matthews:
- Academic CV.
- Official academic transcripts.
- Contact details for two suitable referees.
- A personal statement (750 words maximum) outlining your suitability for the study, what you hope to achieve from the PhD and your research experience to date.
- Any enquiries relating to the project and/or suitability should be directed to Dr Matthews at the address above.
- Applications are invited up to Friday 30 January 2015.

Scholarship Summary

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